Andrographolide isolated from Andrographis paniculata Ness

Andrographis paniculata (Burm.f) Wall. ex Ness: A Potent Antibacterial Plant

Stability of Andrographolide in Andrographis Paniculata under Selected Storage Conditions

Fresh Andrographis paniculata was dried by a thin layer drying technique using hot air at a temperature of 55°C and velocity of 1.0 m/s. The dried sample was then ground and kept in air-tight glass bottles at three selected storage conditions (5±2°C; 25±2°C with 60% ± 5% RH; 30±2°C with (60% ± 5%RH) for three months period. The contents of the active compound andrographolide present in the drie...

Cardiovascular Activity of Labdane Diterpenes from Andrographis paniculata in Isolated Rat Hearts

The dichloromethane (DCM) extract of Andrographis paniculata Nees was tested for cardiovascular activity. The extract significantly reduced coronary perfusion pressure by up to 24.5 ± 3.0 mm Hg at a 3 mg dose and also reduced heart rate by up to 49.5 ± 11.4 beats/minute at this dose. Five labdane diterpenes, 14-deoxy-12-hydroxyandrographolide (1), 14-deoxy-11,12-didehydroandrographolide (2), 14...

Antifungal activity of the extract of Andrographis paniculata and andrographolide

Antifungal activity assay of the methanol extract of the aerial parts of the plant Andrographis paniculata revealed that it exhibits mycelial growth inhibition of Fusarium solani and spore germination inhibition of Alternaria solani. Pure andrographolide present in the methanol extract also exhibited spore germination inhibition of A. solani. Quantitative estimation of andrographolide in the me...

Effect of Signal Compounds on Andrographolide in the Hairy Root Cultures of Andrographis Paniculata

E-mail: [email protected] ABSTRACT: Andrographolide is one of the main active principles in Andrographis paniculata .It exhibits enormous pharmacological effects. Due to this immense value it required more level in pharmaceutical to satisfy the global need. Because it present in a very low level in normal regenerated plant of Andrographis paniculata. Micro propagation is a proven method f...